Atherosclerosis is the major cause of cardiovascular-disease-related death worldwide, resulting from the subendothelial accumulation of lipoprotein-derived cholesterol, ultimately leading to chronic inflammation and the formation of clinically significant atherosclerotic plaques.Oligosaccharides have been widely used in biomedical research and ther
The new classification of drug hypersensitivity reactions (DHRs) is based on phenotypes, endotypes, CHEESE and biomarkers.Immediate and delayed reactions are the clinical phenotypic presentation while endotypes are based on cellular, biological mediators, and biomarkers.Complement activation, cyclooxygenase-1 inhibition, Mas-Related G Protein-Coupl
There are multiple extreme events underway in the Arctic that are beyond previous records: rain in Greenland, Alaska weather variability, and ecosystem reorganizations in the Barents and the northern Bering Sea associated with climate change and sea-ice loss.Such unique extreme events represent a philosophical challenge for interpretation, i.e., a